4 research outputs found
Poročila
Place – an introduction
New money in rural areas. Land investment in Europe and its place impacts
Rethinking Place Branding
The taste of place – a cultural journey into terroir
Kratka kronika nekega leta: obeleževanje naše prve stoletnice
Mednarodna konferenca Skrite geografije
100-letnica rojstva dr. Vladimirja Bračiča in monografija o Halozah
Razvoj podeželja in LEADER: priročnik in mednarodna konferenca
Izzivi in priložnosti multifunkcijskega upravljanja travišč
Mesec prostora 2019
5. Slovenski podeželski parlament: delavnica Mladi in novi kmetje ter podelitev »Nagrade NEWBIE 2018«
Nagrajeni rezultati geografskega proučevanja (funkcionalno) degradiranih območij v letu 201
An oomycete NLP cytolysin forms transient small pores in lipid membranes
Microbial plant pathogens secrete a range of effector proteins that damage host plants and consequently constrain global food production. Necrosis and ethylene-inducing peptide 1-like proteins (NLPs) are produced by numerous phytopathogenic microbes that cause important crop diseases. Many NLPs are cytolytic, causing cell death and tissue necrosis by disrupting the plant plasma membrane. Here, we reveal the unique molecular mechanism underlying the membrane damage induced by the cytotoxic model NLP. This membrane disruption is a multistep process that includes electrostatic-driven, plant-specific lipid recognition, shallow membrane binding, protein aggregation, and transient pore formation. The NLP-induced damage is not caused by membrane reorganization or large-scale defects but by small membrane ruptures. This distinct mechanism of lipid membrane disruption is highly adapted to effectively damage plant cells.Peer reviewe
An oomycete NLP cytolysin forms transient small pores in lipid membranes
Microbial plant pathogens secrete a range of effector proteins that damage host plants and consequently constrain global food production. Necrosis and ethylene-inducing peptide 1-like proteins (NLPs) are produced by numerous phytopathogenic microbes that cause important crop diseases. Many NLPs are cytolytic, causing cell death and tissue necrosis by disrupting the plant plasma membrane. Here, we reveal the unique molecular mechanism underlying the membrane damage induced by the cytotoxic model NLP. This membrane disruption is a multistep process that includes electrostatic-driven, plant-specific lipid recognition, shallow membrane binding, protein aggregation, and transient pore formation. The NLP-induced damage is not caused by membrane reorganization or large-scale defects but by small membrane ruptures. This distinct mechanism of lipid membrane disruption is highly adapted to effectively damage plant cells.Peer reviewe